What Are Polynucleotides for Skin Renewal Treatment?

SadaNews - Beauty clinics are witnessing a surge in the use of polynucleotide injections for skin renewal, smoothing, hydration, and revitalization without altering facial features. Could these injections be an alternative to Botox?

Many videos circulated on social media promote polynucleotide injections as the perfect alternative to Botox, but dermatologists have a different opinion in this regard.

They believe that the effects of these injections are less effective than Botox in combating aging, as they do not treat deep wrinkles or skin sagging. However, they emphasize the importance of their preventive effect, which relies on caring for the inner layers of the skin.

This means that polynucleotide injections do not aim to replace traditional youth-enhancing methods but rather complement a plan to delay the appearance of wrinkles and maintain youthful skin for as long as possible.

Source of This Technique

Currently, polynucleotide injections are considered one of the most promising treatments in aesthetic medicine, as they improve skin quality without making any changes to facial features. Polynucleotides are defined as highly pure natural fragments of DNA. They are primarily derived from salmon fish cells, and can also be extracted from trout or some plant sources; however, the type derived from salmon remains the most effective to date. Their structure, which is very similar to human DNA, provides them with excellent biocompatibility and complete safety. When injected into the skin, they play a real role in activating cells, enhancing their natural renewal mechanism.

Their Effect

Polynucleotides work at several levels:

• Deep biological hydration: They retain water in the depths of the dermis, enhancing tissue softness and elasticity.

• Cellular stimulation: They activate fibroblasts responsible for producing collagen, elastin, and hyaluronic acid.

• Antioxidant effect: They neutralize free radicals, reducing oxidative stress and delaying skin aging.

• Repair effect: These injections were initially used in the medical field to promote wound healing, as they help the skin regenerate and make it tighter and more radiant.

Their Effect Compared to Hyaluronic Acid

Hyaluronic acid focuses on filling and moisturizing the skin's surface, whereas polynucleotides do not provide artificial volume but work deeply within the tissues by stimulating the natural production of collagen and elastin. Thus, they do not aim to plump the skin instantly, but to rejuvenate it gradually and permanently. This makes this treatment suitable for anyone wishing to:

• Improve the condition of dry, dull, and fragile skin.

• Prevent and treat mild to moderate skin sagging.

• Reduce fine lines and enhance the radiance of the eye area.
This treatment can also be used as a complement to other cosmetic treatments, including hyaluronic acid, laser, and facelift procedures.

Expected Results

This treatment involves injecting the skin with fine needles during sessions lasting between 15 and 30 minutes each. It is usually recommended to follow a protocol of two to four sessions at intervals of 3 to 4 weeks, followed by maintenance sessions once or twice a year. The results are gradual and cumulative; after the first session, there is an improvement in skin radiance and hydration, becoming more resilient, denser, and elastic in the following weeks. The results stabilize over several months and are accompanied by a continuous improvement in skin quality.

Necessary Precautions

To enhance the effectiveness of this treatment, it is essential to follow some guidelines during the first 24 hours after application:

• Do not wash the face.

• Do not apply makeup.

• Avoid any activity that causes sweating, such as sports, saunas, steam rooms, and exposure to excessive heat.
These measures allow the injected product to remain in the fine channels within the skin and maintain its effect instead of being expelled from the body through sweating.

The results of this treatment last between 6 to 12 months and are suitable for all ages due to their preventive effect, which stimulates skin cells.