Can Omega-3 be Taken with Vitamin E?

SadaNews - Many people wonder whether it is safe or beneficial to take omega-3 fatty acid supplements with vitamin E at the same time, especially with their widespread use for supporting heart health, immunity, and combating inflammation. Some studies suggest that combining these two supplements may help improve insulin resistance and reduce oxidative stress, but scientific evidence is still limited.

A report from "Verywell Health" highlights the benefits and risks of combining omega-3 and vitamin E, and the safest usage methods, according to the latest medical research.

Can omega-3 and vitamin E supplements be taken together?

Omega-3 fatty acids and vitamin E supplements can be taken at the same time, but the potential benefits of combining them have not been studied sufficiently to date.

What does the research say?

Some limited studies indicate potential benefits, but the overall effects remain uncertain:

Insulin Resistance: A small study showed that the combination of the two supplements may improve insulin levels and insulin resistance in individuals with coronary artery disease, but more research is needed.

Cholesterol: A systematic review and meta-analysis found that taking the two supplements together may lower levels of very-low-density lipoprotein (VLDL) cholesterol, a type of cholesterol that transports triglycerides to tissues. However, no significant effects were observed on other lipid markers.

Oxidative Stress: A meta-analysis indicated that combining omega-3 and vitamin E may reduce oxidative stress by increasing nitric oxide levels, enhancing antioxidant effects, and lowering levels of malondialdehyde (a marker of oxidative stress).

Advice before taking supplements

When considering taking any of these supplements or combining them, it's important to discuss the following matters with a doctor or healthcare provider:

- Purpose of use.

- The most suitable type of product (preferably those tested by an independent entity).

- The appropriate dosage.

- Potential drug interactions.

- Expected outcome.

Since both supplements may increase the risk of bleeding, it is crucial to consult a doctor, especially if you are taking anticoagulant medications or have bleeding disorders.

What are omega-3 fatty acids?

Omega-3 fatty acids are polyunsaturated fatty acids known for their anti-inflammatory effects.

The most common types are:

- Alpha-linolenic acid (ALA)

- Eicosapentaenoic acid (EPA)

- Docosahexaenoic acid (DHA)

Omega-3 fatty acids are found in natural foods and also in dietary supplements. Among the best dietary sources are:

- Fatty fish: such as salmon, herring, sardines, mackerel, trout, shellfish, bass, cod, and tuna.

- Seafood: such as shrimp, lobster, and scallops.

- Nuts: especially walnuts.

- Seeds: such as flaxseeds and chia seeds.

- Oils: like flaxseed oil, canola oil, and soybean oil.

- Legumes: such as edamame, red beans, and baked beans.

What is the role of omega-3 fatty acids in the body?

Research indicates that omega-3 fatty acids, whether from food or supplements, may help reduce the following:

- The risk of heart diseases.

- Elevated triglyceride levels (especially when taking prescribed fish oil supplements).

- The risk of premature birth or low birth weight in pregnant women.

- Symptoms of rheumatoid arthritis (RA).

A recent meta-analytical study (Bilgundi et al., Nutrition Research, 2024) suggests that DHA may be associated with improved health for both mother and fetus during pregnancy.